Tsartsali Lemonia Pediatrician

PhD Thesis

• 2008-2011: PhD Thesis (grade A) with the title: «Polymorphisms in the Hypothalamic-Pituitary-Adrenal Axis and adrenal insufficiency in children on long term use of inhaled corticosteroids»

Board Member

• Member of the Greek Pediatric Society since 1998

• Member of the European Respiratory Society since 2007

• Member of the Greek Pediatric Pulmonology Society since 2008

• Member of the Athens Medical Council since1996

• Member of the Greek Medical Council since1996

• Member of the British General Medical Council (Certificate of Specialty Registration) since 2006

Professional Experience

Experience after Pediatric Specialty title

• 01/08/2012-today: Associate Director, Pediatric Department MITERA CHILDREN’S HOSPITAL

• 01/08/2009 – 0/08/2012: Scientific Associate, Pediatric Department Maternity Hospital LITO

• 14/02/2009 – 0/08/2012: Consultant Pediatrician, 1^st Pediatric Department «IATRIKO ATHINON» (Director: Prof. Spyrides)

• 09/2008-02/2009: Scientific Associate, Pediatric Pulmonology Clinic, «AGIA SOFIA» Children’s Hospital (Director: Prof: G. Chrousos)

• 15/09/2008 – today: Private Clinic

• 01/01/2008 – 15/08/2008: Registrar, Pediatric Department, «Cromwell Hospital», London, UK (Director:Prof: Howards)

• 15/02/2007 – 15/08/2008: Specialization (Clinical Research Fellow) in Pediatric Pulmonology, Royal Brompton Hospital, Imperial College, London, UK (Director: Prof. Andrew Bush)

• 05/2006-01/2007: Scientific Associate, Pediatric Pulmonolgy and Allergy Clinic, Penteli’s Children’s Hospital (Director: K. Priftis)

• 06/10/2006 – 31/01/2007: Consultant Pediatrician, 2^nd Pediatric Department «IATRIKO ATHINON» (Director: Prof. Th. Karpathios)

Pediatric Secialty

• 14/08/1998 – 13/08/2000: Pediatric Department of General Hospital of Volos «Αchilopoulio» (Director: Ε. Petsiava)

• 14/08/2000 – 15/02/2001: Medical Center of Zagora Piliou (Director: Α. Akrivos).

• 27/03/2003 – 23/10/2005: 1^st Pediatric Department, University of Athens, «Agia Sofia» Children’s Hospital (Director: Prof. G. Chrousos)

EDUCATION EXPERIENCE:

• Responsible for 5^th year medical students’ education in Pediatrics (NICOSIA and EUC Universities of Cyprus)

• Participation in the education of students of the Medical School of Athens during my education in Pediatric Specialty at the 1^st Pediatric Department, «Agia Sofia» Children’s Hospital

• Teaching lessons in Pediatrics («Children with visual impairments», «Basics in Pediatrics») for students in biomedical sciences (public college) (2001)

Clinical & Research Interest

Clinical interest:

• Follow up of general pediatric patients hospitalized in the Pediatric Department of MITERA CHILDREN’S HOSPITAL

• Follow up of children with several respiratory problems with special interest in pediatric asthma

 
Research interest:

• Use of several biomarkers for the follow up of children with mild to moderate persistent asthma (exhaled NO, exhaled breath condensate (EBC), sputum induction) and their correlation with the “Asthma Control Test”

• Treatment Protocol for children with “difficult to treat asthma”

• Assessment of airway inflammation in patients with cystic fibrosis

• The normal development of the basement membrane of the bronchial tree

• Efficacy and safety of formoterol when administered with the «Elpenhaler» device (has been financed by the pharmaceutical company ELPEN)

• Polymorphisms in the Hypothalamic – Pituitary- Adrenal axis and adrenal suppression in asthmatic children on long term use of inhaled corticosteroids (has been financed by the pharmaceutical company GlaxoSmithKline)

• Multicenter Epidemiological Study to assess the prevalence of respiratory syncytial cirus and the evaluation of risk factors in children less than 2 years of age hospitalized for respiratory tract infection in Greece 2012-2013 (financed by Abbot Laboratories Greece)

• Multicenter non interventional study «PNEUSIS» from MSD pharmaceutical company of pneumococcal serotype prevalence and antimicrobial resistance in pediatric patients with pneumococcal infections in Greece {2022-2024)

Awards

• Scholarship (after exams) founded by Papadaki’s Greek foundation for my studies in the Medical School (1990-1996)

• Award of excellence at an honorary event by the dean and president of the Medical School of Athens for my excellent performance in the medical school

• Pulmonology research fellowship award founded by GlaxoSmithKlein company for my PhD project: ”Polymorphisms in the hypothalamic-pituitary-adrenal axis and adrenal suppression in asthmatic children on long term use of inhaled corticosteroids” during the 15^th Panhellenic Conference on Thoracic Diseases (2-5 November 2006, Crete)

• Award for best studies of the 29^th Panhellenic Gastroenterology Conference. Annals of Gastroenterology 2009, Vol 22(Suppl):10 (Oral Presentation)

Recent Publications

Publications in international journals (MEDLINE και EMBASE indexed)

• Passive smoking impairs Histone Deacetylase-2 in children with severe asthma. Yoshiki Kobayashi, Cara Bossley, Atul Gupta, Kenichi Akashi, Lemonia Tsartsali, Nicolas Mercado, Peter J. Barnes, Andrew Bush, Kazuhiro Ito. Chest. 2014 Feb; 145(2): 305-312.

• Longitudinal relationship between sputum eosinophils and exhaled nitric oxide in children with asthma. Fleming L, Tsartsali L, Wilson N, Regamey N, Bush A. Am J Respir Crit Care Med 2013 1; 188(3): 400-2

• Pediatric severe asthma is characterized by eosinophilia and remodeling without T(H)2 cytokines. Bossley CJ, Fleming L, Gupta A, Regamey N, Frith J, Oates T, Tsartsali L, Lloyd CM, Bush A, Saglani S. J Allergy Clin Immunol 2012 Apr; 129(4): 974-82.

• Sputum inflammatory phenotypes are not stable in children with asthma. Fleming L, Tsartsali L, Wilson N, Regamey N, Bush A. Thorax 2012 Aug; 67(8):675-81.

• Association of hypothalamic-pituitary-adrenal axis-related polymorphisms with stress in asthmatic children on inhaled corticosteroids. Tsartsali L, Papadopoulos M, Lagona E, Papadimitriou A, Kanaka-Gantenbein C, Louizou E, Kastania A, Priftis KN, Chrousos G. Neuroimmunomodulation 2012; 19(2):88-95.

• Distinct patterns of inflammation in the airway lumen and bronchial mucosa of children with cystic fibrosis. Regamey N, Tsartsali L, Hilliard TN, Fuchs O, Tan HL, Zhu J, Qiu YS, Alton EW, Jeffery PK, Bush A, Davies JC. Thorax 2012 Feb; 67(2): 164-70.

• Detection of gastric premalignant lesions using a Narrow Band Imaging and targeted biopsies protocol compared with a White Light Endoscopy and the updated Sydney protocol. Xirouchakis E, Laoudi F, Tsartsali L, Spiliadi C, Christoforidis P, Georgopoulos Digestive Disease and Science 2012

• Development of the bronchial epithelial reticular basement membrane: relationship to epithelial height and age. Tsartsali L, Hisslop AA, McKay K, James AL, Elliot J, Zhu J, Rosenthal M, Payne DN, Jeffery PK, Bush A, Saglani S. Thorax 2011 Apr; 66(4):280-5.

• Corticosteroid responsiveness and clinical characteristics in childhood difficult asthma. Bossley CJ, Saglani S, Kavanagh C, Payne DN, Wilson N, Tsartsali L, Rosenthal M, Balfour-Lynn IM, Nicholson AG, Bush A. ERJ 2009 Nov; 34(5): 1052-9.

• Skin biopsy for the diagnosis of Alport Syndrome. Lagona E, Tsartsali L, Kostaridou S, Skiathitou A, Georgaki E, Sotsiou F. Hippokratia 2008 Apr; 12(2):116-118.