Christopoulos George Obstetrician - Gynecologist

Professional Experience

• Consultant Obstetrician and Gynaecologist University College London Hospitals NHS Foundation Trust, London, UK

• Medical Director, Lead Consultant Gynaecologist Thames Valley Fertility IVF Unit, Maidenhead, UK

• Honorary Senior Lecturer, Imperial College London, UK

• Subspecialty Registrar in Reproductive Medicine and Surgery Imperial College Healthcare NHS Trust

• IVF Clinical Research Fellow IVF Unit, Hammersmith Hospital, Imperial College Healthcare NHS Trust

• Completion of the London Deanery School of Obstetrics and Gynaecology Specialty Training (2007-2017)

Qualifications

• Certificate of Sub-Specialist Accreditation in Reproductive Medicine. Royal College of Obstetricians and Gynaecologists.

• Advanced Training Skills Module (ATSM) in Subfertility and Reproductive Health. Royal College of Obstetricians and Gynaecologists.

• Advanced Training Skills Module (ATSM) in Advanced Labour Ward Practice. Royal College of Obstetricians and Gynaecologists.

• British Fertility Society Assisted Conception Certification. 

• British Fertility Society Pelvic Ultrasound Certification.

• British Fertility Society Embryo Transfer/IUI Certification. 

• Postgraduate Diploma (PGDip) in Advanced Gynaecological Endoscopy. University of Surrey.

• MRCOG. Royal College of Obstetricians and Gynaecologists.

• Diploma of the Faculty of Reproductive and Sexual Health (DFRH). Royal College of Obstetricians and Gynaecologists.

• Medical Degree (Ptychio Iatrikes Athens 2003), Medical School of the University of Athens, Greece.

Thesis

MD(Res) ‘The use of kisspeptin as a novel oocyte maturation trigger in IVF’  Department of Endocrinology and Diabetes, Imperial College London.

Registrations

• General Medical Council, Full registration, Registration Number: 6083739

• European Society of Human Reproduction and Embryology

• American Society for Reproductive Medicine

• British Fertility Society

• British Menopause Society

• British Society for Gynaecological Endoscopy

Education Experience

As an Honorary Senior Lecturer at Imperial College London and faculty member of the MSc in Reproductive and Developmental Biology, Dr Christopoulos delivers lectures and supervises BSc students during their assigned projects. In his role as the Clinical Lead at Thames Valley Fertility, he regularly organised CPD-accredited training days for gynaecologists and general practitioners.

Clinical and Research Interest

Clinical Interest:

Dr Christopoulos is an accredited specialist in laparoscopic gynaecological surgery and his special interests include reproductive endocrinology, menopause and the management of male infertility. As an NHS Consultant at University College Hospital and a clinical director at Thames Valley Fertility he has helped thousands of women and couples going through fertility treatment including IVF, ICSI, oocyte donation and fertility preservation. His philosophy has always been to tailor medical treatment to the individual needs of women and couples through a clear and evidence-based approach.

Research Interest:

Mr Christopoulos has significant research background. He has published extensively in the field of assisted conception and his research interests include uterine fibroids, polycystic ovarian syndrome and the prevention of ovarian hyper stimulation syndrome. His MD at Imperial College London focused on the use of novel medication, which aimed to decrease complications and improve the safety profile of IVF cycles. This research project received widespread attention from the scientific community and the media both at national and international level.

Awards

• The Clinicians Award for Best Presentation (British Fertility Society Meeting 2017) For the oral presentation ‘Can the transfer of a genetically affected embryo ever be justified? Questions of autonomy and welfare of the child in the case of the transfer of an embryo affected with osteogenesis imperfecta’

• The Laurence Shaw Medal Award (Winter Reproductive Symposium 2016) for the oral presentation ‘The use of kisspeptin-54 in women at high risk of OHSS’

• The Fertility Society of Australia Exchange Award (ESHRE Annual Meeting 2014) for the oral presentation ‘Kisspeptin–a novel physiological trigger for oocyte maturation in IVF’

Books

Chapter Title: Fertility

‘Breast Cancer Survivorship’ Editors: Ring and Parton, Royal Marsden Hospital

Recent Publications

1. Abbara A, Islam R, Clarke SA, Jeffers L, Christopoulos G, Comninos AN, Salim R, Lavery SA, Vuong TNL, Humaidan P, Kelsey TW, Trew GH, Dhillo WS. Clinical parameters of ovarian hyperstimulation syndrome following different hormonal triggers of oocyte maturation in IVF treatment. Clinical Endocrinology (Oxford). 2018 Jun;88(6):920-927. doi: 10.1111/cen.13569.

2. Owens LA, Abbara A, Lerner A, O’floinn S, Christopoulos G, Khanjani S, Islam R, Hardy K, Hanyaloglu AC, Lavery SA, Dhillo WS, Franks S. The direct and indirect effects of kisspeptin-54 on granulosa lutein cell function. Human Reproduction 2018 Feb 1;33(2):292-302. doi: 10.1093/humrep/dex357.

3. Christopoulos G, Vlismas A, Salim R, Islam R, Trew G, Lavery S.  Fibroids not distorting the uterine cavity and IVF success rates: an observational study using extensive matching criteria. British Journal of Obstetrics and Gynaecology (BJOG). 2017 Mar;124(4):615-621

4. Christopoulos G, Vlismas A, Carby A, Lavery S, Trew G. GnRH agonist trigger with intensive luteal phase support vs. human chorionic gonadotropin trigger in high responders: an observational study reporting pregnancy outcomes and incidence of ovarian hyperstimulation syndrome. Human Fertility 2016;19(3):199-206

5. Christopoulos G, Vlismas A, Barsoum-Derias E, El-Shawarby S, Trew G, Lavery S. Rescue hCG to treat empty follicle syndrome after the use of a GnRH agonist as oocyte maturation trigger: first report on fresh embryo transfer and clinical pregnancy. Human Fertility 2015;18(4):248-52

6. Abbara A, Jayasena CN, Christopoulos G, Narayanaswamy S, Izzi-Engbeaya C, Nijher GM, Comninos AN, Peters D, Buckley A, Ratnasabapathy R, Prague JK, Salim R, Lavery SA, Bloom SR, Szigeti M, Ashby DA, Trew GH, Dhillo WS. Efficacy of Kisspeptin-54 to Trigger Oocyte Maturation in Women at High Risk of Ovarian Hyperstimulation Syndrome (OHSS) During In Vitro Fertilization (IVF) Therapy.  Journal of Clinical Endocrinology and Metabolism 2015;100(9):3322-31

7. Jayasena CN, Abbara A, Comninos AN, Nijher GMK, Christopoulos G, Narayanaswamy S, Sridharan M, Mason A, Warwick J, Ashby D, Ghatei M, Bloom SR, Carby A, Trew G, Dhillo W. Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilisation. Journal of Clinical Investigations 2014; 124(8): 3667-77

8. Christopoulos G, Kelly T, Lavery S, Trew G. Surgical skills of specialty trainees in emergency gynaecological laparoscopic procedures: A national UK survey. Journal of Obstetrics and Gynaecology 2014; 34(5):435-8

9. Christopoulos G, Kelly, T. Letter to the Editor: An update on the diagnosis and management of ovarian torsion. The Obstetrician & Gynaecologist 2013, 15: 137

10. Christopoulos G, Goubet S, Kelly T. Interleukin-6 for the diagnosis of ovarian torsion: a systematic review and meta-analysis. Journal of Obstetrics and Gynaecology 2013; 33(5):438-41